Potential activity of Traditional Chinese Medicine against Ulcerative colitis: A review

Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course,...

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Published inJournal of ethnopharmacology Vol. 289; no. NA; p. 115084
Main Authors Liu, Yang, Li, Bao-Guo, Su, Yu-Hua, Zhao, Ruo-Xi, Song, Peng, Li, Hui, Cui, Xin-Hai, Gao, Hong-Mei, Zhai, Run-Xiang, Fu, Xian-Jun, Ren, Xia
Format Journal Article
LanguageEnglish
Published Ireland Elsevier B.V 10.05.2022
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Abstract Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC. This review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC. We performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research. There are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC. TCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC. [Display omitted]
AbstractList Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC. This review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC. We performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research. There are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC. TCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC. [Display omitted]
Ethnic pharmacological relevance Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC. Aim of this review This review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC. Methods: We performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research. Results: There are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC. Conclusion: TCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC. Graphical abstract Image 1
Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC.ETHNIC PHARMACOLOGICAL RELEVANCEPlant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC.This review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC.AIM OF THIS REVIEWThis review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC.We performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research.METHODSWe performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research.There are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC.RESULTSThere are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC.TCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC.CONCLUSIONTCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC.
Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC. This review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC. We performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research. There are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC. TCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC.
Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a chronic nonspecific inflammatory bowel disease listed as one of the modern refractory diseases by the World Health Organization, has a long course, is challenging to cure, and is prone to cause cancer. Recent years have witnessed a growing trend of applying traditional Chinese medicine (TCM) to UC. This review presents an overview of the pathogenesis of UC and reports the therapeutic effect of TCM on UC (including TCM prescriptions, single TCM, and treatments using TCM ingredients) to provide a theoretical basis for the use of TCM in treating UC. We performed a collection and collation of relevant scientific articles from different scientific databases regarding TCM and its usefulness in treating UC. In this paper, the therapeutic effect of TCM is summarized and analyzed according to the existing experimental and clinical research. There are positive signs that TCM primarily regulates inflammatory cytokines, intestinal flora, and the immune system, and also protects the intestinal mucosa. Hence, it can play a role in treating UC. TCM has a definite curative effect in the treatment of UC. It can alleviate and treat UC in a variety of ways. We should take syndrome differentiation and treatment differentiation as the basis. With the help of modern medicine, TCM's clinical curative effects can be enhanced for the treatment of UC.
ArticleNumber 115084
Author Fu, Xian-Jun
Li, Bao-Guo
Cui, Xin-Hai
Gao, Hong-Mei
Ren, Xia
Li, Hui
Liu, Yang
Zhao, Ruo-Xi
Song, Peng
Su, Yu-Hua
Zhai, Run-Xiang
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  organization: College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China
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  surname: Li
  fullname: Li, Bao-Guo
  organization: College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China
– sequence: 3
  givenname: Yu-Hua
  surname: Su
  fullname: Su, Yu-Hua
  organization: Department of Immunology and Rheumatology, Affiliated Hospital of Weifang Medical College, Weifang, 261000, China
– sequence: 4
  givenname: Ruo-Xi
  surname: Zhao
  fullname: Zhao, Ruo-Xi
  organization: TCM Specialty Class 4, 2018, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China
– sequence: 5
  givenname: Peng
  surname: Song
  fullname: Song, Peng
  organization: College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China
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  orcidid: 0000-0002-8573-3849
  surname: Li
  fullname: Li, Hui
  organization: Marine Traditional Chinese Medicine Research Center, Qingdao Academy Shandong University of Traditional Chinese Medicine, Qingdao, 266114, China
– sequence: 7
  givenname: Xin-Hai
  surname: Cui
  fullname: Cui, Xin-Hai
  organization: College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China
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  givenname: Hong-Mei
  surname: Gao
  fullname: Gao, Hong-Mei
  organization: Marine Traditional Chinese Medicine Research Center, Qingdao Academy Shandong University of Traditional Chinese Medicine, Qingdao, 266114, China
– sequence: 9
  givenname: Run-Xiang
  surname: Zhai
  fullname: Zhai, Run-Xiang
  organization: Marine Traditional Chinese Medicine Research Center, Qingdao Academy Shandong University of Traditional Chinese Medicine, Qingdao, 266114, China
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  orcidid: 0000-0001-8347-628X
  surname: Ren
  fullname: Ren, Xia
  email: 1989renxia@163.com
  organization: Marine Traditional Chinese Medicine Research Center, Qingdao Academy Shandong University of Traditional Chinese Medicine, Qingdao, 266114, China
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Keywords Traditional Chinese medicine
Therapeutic drugs
Mechanism
Ulcerative colitis
Language English
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Snippet Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases. Ulcerative colitis (UC), a...
Ethnic pharmacological relevance Plant materials are used as complementary and alternative therapies all over the world for the treatment of various diseases....
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SubjectTerms Animals
biomedical research
Colitis, Ulcerative - drug therapy
cytokines
Cytokines - metabolism
Drugs, Chinese Herbal - pharmacology
Gastrointestinal Microbiome - drug effects
Humans
immune system
intestinal microorganisms
intestinal mucosa
Intestinal Mucosa - drug effects
Mechanism
Medicine, Chinese Traditional - methods
Oriental traditional medicine
pathogenesis
Therapeutic drugs
Traditional Chinese medicine
Ulcerative colitis
World Health Organization
Title Potential activity of Traditional Chinese Medicine against Ulcerative colitis: A review
URI https://dx.doi.org/10.1016/j.jep.2022.115084
https://www.ncbi.nlm.nih.gov/pubmed/35134488
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