Alteration in glucose homeostasis and persistence of the pancreatic clock in aged mPer2Luc mice

• Published in: Scientific reports Vol. 8; no. 1; p. 11668
• Main Authors: Novosadová, Zuzana, Polidarová, Lenka, Sládek, Martin, Sumová, Alena
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.08.2018
• Subjects: 13; 13/106; 38; 38/39; 38/5; 38/77; 631/443/319; 692/163/2743/137/773; Humanities and Social Sciences; multidisciplinary; Science; Science (multidisciplinary)

The physiological function of the pancreas is controlled by the circadian clock. The aim of this study was to determine whether aging-induced changes in glucose homeostasis affect properties of the circadian clock in the pancreas and/or its sensitivity to disturbances in environmental lighting condi...