A Potential Role for the Receptor for Advanced Glycation End-Products (RAGE) in the Development of Secondhand Smoke-Induced Chronic Sinusitis

• Published in: Current Issues in Molecular Biology Vol. 46; no. 1; pp. 729 - 740
• Main Authors: Robin, Hannah, Trudeau, Courtney, Robbins, Adam, Chung, Emily, Rahman, Erum, Gangmark-Strickland, Olivia, Licari, Frank W, Winden, Duane R, Orr, Dan L, Arroyo, Juan A, Reynolds, Paul R
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.01.2024
• Subjects: Health aspects; Inflammation; Passive smoking; Proteases; RAGE; sinusitis; Tetracycline; Tetracyclines; sinusitis; inflammation; RAGE

Chronic sinusitis (CS) is characterized by sinonasal inflammation, mucus overproduction, and edematous mucosal tissue. CS impacts one in seven adults and estimates suggest up to 15% of the general U.S. population may be affected. This research sought to assess a potential role for receptors for adva...