Molecular imaging in living subjects: seeing fundamental biological processes in a new light

• Published in: Genes & development Vol. 17; no. 5; pp. 545 - 580
• Main Authors: Massoud, Tarik F., Gambhir, Sanjiv S.
• Format: Journal Article
• Language: English
• Published: United States 01.03.2003
• Subjects: Animals; Forecasting; Genes, Reporter; Genetic Therapy; Humans; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Mice; Microscopy, Fluorescence - instrumentation; Microscopy, Fluorescence - methods; Molecular Biology - methods; Molecular Probe Techniques; Radioisotopes; Rats; Tomography, Emission-Computed - instrumentation; Tomography, Emission-Computed - methods; Tomography, X-Ray Computed - instrumentation; Tomography, X-Ray Computed - methods

The emergence of molecular imaging strategies is largely due to recent unprecedented advances in molecular and cell biology techniques, the use of transgenic animal models, availability of newer imaging drugs and probes that are highly specific, and successful development of small-animal imaging ins...