DNA Microarray analysis of complex biologic processes

• Published in: Journal of the American Society of Nephrology Vol. 12; no. 5; pp. 1072 - 1078
• Main Authors: KURELLA, Manjula, HSIAO, Li-Li, YOSHIDA, Takumi, RANDALL, Jeffrey D, CHOW, Gary, SARANG, Satinder S, JENSEN, Roderick V, GULLANS, Steven R
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.05.2001
• Subjects: Biological and medical sciences; Drug Design; Gene Expression Profiling; Humans; Investigative techniques, diagnostic techniques (general aspects); Kidney Diseases - drug therapy; Kidney Diseases - genetics; Medical sciences; Miscellaneous. Technology; Oligonucleotide Array Sequence Analysis; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Phenotype; Human; Exploration; Technique; Gene; Genetic determinism; DNA

DNA microarrays, or gene chips, allow surveys of gene expression, (i.e., mRNA expression) in a highly parallel and comprehensive manner. The pattern of gene expression produced, known as the expression profile, depicts the subset of gene transcripts expressed in a cell or tissue. At its most fundame...