Hidradenitis Suppurativa Is Characterized by Dysregulation of the Th17:Treg Cell Axis, Which Is Corrected by Anti-TNF Therapy - Moran, Barry; Sweeney, Cheryl M.; Hughes, Rosalind; Malara, Anna; Kirthi, Shivashini; Tobin, Anne-Marie; Kirby, Brian; Fletcher, Jean M. (Journal of investigative dermatology, 2017)
Keywords: Adult; Biopsy, Needle; Case-Control Studies; Cells, Cultured - drug effects; Cohort Studies; Female; Hidradenitis Suppurativa - drug therapy; Hidradenitis Suppurativa - immunology; Hidradenitis Suppurativa - pathology; Humans; Immunity, Cellular - drug effects; Immunity, Cellular - physiology; Immunohistochemistry; Interleukin-17 - immunology; Interleukin-17 - metabolism; Male; Reference Values; T-Lymphocytes, Regulatory - drug effects; T-Lymphocytes, Regulatory - immunology; T-Lymphocytes, Regulatory - metabolism; Th17 Cells - immunology; Th17 Cells - metabolism; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Tumor Necrosis Factor-alpha - pharmacology; PBS; PG; Treg; Th cell; HS; PBMC; TNF