Blood-based analysis of 84 microRNAs identifies molecules deregulated in individuals with type-2 diabetes, risk factors for the disease or metabolic syndrome

• Published in: Diabetes research and clinical practice Vol. 164; p. 108187
• Main Authors: Avgeris, Margaritis, Kokkinopoulou, Ioanna, Maratou, Eirini, Mitrou, Panayota, Boutati, Eleni, Scorilas, Andreas, Fragoulis, Emmanuel G., Christodoulou, Maria-Ioanna
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.06.2020
• Subjects: Insulin-pathway; miRNAs; Peripheral blood; RT-qPCR array; Type-2 diabetes; Type-2 diabetes; Insulin-pathway; RT-qPCR array; miRNAs; Peripheral blood

Micro-RNAs (miRNAs) are implicated in insulin-signaling and the development of type-2 diabetes (T2D). Their deregulated expression is mostly described in the pancreas, liver, skeletal muscle, or adipose tissue of diabetic animals. Relevant studies in humans are limited due to difficulties in accessi...