Research of childhood tuberculosis in suspected populations by molecular methods: A multicenter study in China

• Published in: Frontiers in cellular and infection microbiology Vol. 12; p. 1018699
• Main Authors: Li, Chunling, Wang, Shifu, Yu, Hui, Wang, Jiangxia, Deng, Jikui, Wang, Hongmei, Hua, Chunzhen, Zhuo, Zhiqiang, Chen, Lei, Hao, Jianhua, Gao, Wei, Zhang, Hong, Zhang, Ting, Xu, Hongmei, Wang, Chuanqing
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.10.2022
• Subjects: Adolescent; Cellular and Infection Microbiology; Child; Child, Preschool; children; CPA; extrapulmonary tuberculosis; Humans; molecular; Mycobacterium tuberculosis - genetics; pulmonary tuberculosis; Reproducibility of Results; Sensitivity and Specificity; Sputum - microbiology; Tuberculosis - diagnosis; Tuberculosis - epidemiology; Tuberculosis, Pulmonary - diagnosis; Tuberculosis, Pulmonary - epidemiology; pulmonary tuberculosis; molecular; CPA; children; extrapulmonary tuberculosis

The research of childhood tuberculosis is inadequate in china. The cross-priming amplification (CPA) of specific DNA in clinical samples is increasingly adopted for the diagnosis of childhood tuberculosis. In this study, a multicenter research was performed to investigate the incidence and character...