Pressed Lateral Flow Assay Strips for Flow Delay-Induced Signal Enhancement in Lateral Flow Assay Strips

• Published in: Biochip journal Vol. 16; no. 4; pp. 480 - 489
• Main Authors: Park, Se Been, Shin, Joong Ho
• Format: Journal Article
• Language: English
• Published: Seoul The Korean BioChip Society (KBCS) 01.12.2022; Springer Nature B.V
• Subjects: Antibodies; Antigens; Assaying; Biomedical Engineering and Bioengineering; Biotechnology; C-reactive protein; Chemistry; Chemistry and Materials Science; COVID-19; Flow velocity; Nanoparticles; Original Article; Quantum dots; Strip; South Korea; United Kingdom > UK; United States > US; Germany; COVID-19; Lateral flow assay; Signal enhancement; Immunoassay; C-reactive protein

This paper proposes that the signal intensity of a lateral flow assay (LFA) strip can be increased by pressing the top of the strip, effectively reducing its flow rate. The reduced flow rate allows more time for antigen–antibody interactions to occur, resulting in increased signal intensity and an i...