From clinic to mechanism: Proteomics‐based assessment of angiogenesis in adrenal pheochromocytoma

• Published in: Journal of cellular physiology Vol. 234; no. 12; pp. 22057 - 22070
• Main Authors: Sun, Fukang, Zhuo, Ran, Ma, Wenming, Yang, Da, Su, Tingwei, Ye, Lei, Xu, Danfeng, Wang, Weiqing
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.12.2019
• Subjects: Angiogenesis; Bioinformatics; Biomarkers; Blood vessels; Chromaffin cells; Computed tomography; Hypoxia; Immunohistochemistry; Liquid chromatography; Mass spectrometry; Mass spectroscopy; microvessel density; Pheochromocytoma; Polymerase chain reaction; Proteins; Proteomics; quantitative proteomics; Regression analysis; Surgery; Tumors; computed tomography; microvessel density; pheochromocytoma; angiogenesis; quantitative proteomics

Adrenal pheochromocytoma (PCC) is a very rare tumor that stems from chromaffin cells, which can develop into malignant tumor. During the operation, abundant blood vessels were often observed in PCC than other adrenal tumors, which increases the difficulty and risk of the surgery. Therefore, it is im...