Diabetes impacts prediction of cirrhosis and prognosis by non‐invasive fibrosis models in non‐alcoholic fatty liver disease

• Published in: Liver international Vol. 38; no. 10; pp. 1793 - 1802
• Main Authors: Bertot, Luis C., Jeffrey, Gary P., de Boer, Bastiaan, MacQuillan, Gerry, Garas, George, Chin, Justin, Huang, Yi, Adams, Leon A.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.10.2018
• Subjects: Accuracy; Adult; Aged; Australia - epidemiology; Biopsy; Carcinoma, Hepatocellular - mortality; Carcinoma, Hepatocellular - surgery; Cirrhosis; Cohort analysis; cohort study; Death; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - pathology; Disease Progression; Fatty liver; Female; Fibrosis; fibrosis models; Follow-Up Studies; Health risks; Hepatocellular carcinoma; Humans; Kaplan-Meier Estimate; Liver; Liver - pathology; Liver - surgery; Liver cirrhosis; Liver Cirrhosis - complications; Liver diseases; Liver Neoplasms - mortality; Liver Neoplasms - surgery; Liver Transplantation; Male; Mathematical models; Middle Aged; Model accuracy; Mortality; Non-alcoholic Fatty Liver Disease - complications; Non-alcoholic Fatty Liver Disease - pathology; Patients; Predictions; Prognosis; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Transplantation; Australia; cohort study; fibrosis models; diabetes; cirrhosis; hepatocellular carcinoma

Background & Aims Non‐alcoholic fatty liver disease (NAFLD) patients with diabetes are at increased risk of cirrhosis and liver‐related death, and thus accurate fibrosis assessment in these patients is important. We examined the ability of non‐invasive fibrosis models to determine cirrhosis and...