Real‐time activation of central cholinergic circuits during recognition memory

• Published in: The European journal of neuroscience Vol. 45; no. 11; pp. 1485 - 1489
• Main Authors: Bonnì, Sonia, Ponzo, Viviana, Di Lorenzo, Francesco, Caltagirone, Carlo, Koch, Giacomo, Thut, Gregor
• Format: Journal Article
• Language: English
• Published: France Wiley Subscription Services, Inc 01.06.2017
• Subjects: Acetylcholine; Adult; Central Nervous System - cytology; Central Nervous System - physiology; Cholinergic Neurons - physiology; Circuits; Evoked potentials; Evoked Potentials, Motor; Facial Recognition; Humans; Latency; Magnetic fields; memory; Mental task performance; Motor evoked potentials; Motor task performance; Random Allocation; Reaction Time; retrieval; Sensory neurons; short latency afferent inhibition; Transcranial Magnetic Stimulation; Visual pathways; short latency afferent inhibition; memory; acetylcholine; retrieval

Short latency afferent inhibition (SAI) is a paired‐pulse transcranial magnetic stimulation (TMS) protocol that consists in the inhibition of the motor evoked potentials (MEPs) by afferent sensory impulses. SAI is thought to be mediated by cholinergic projections over M1 and can be considered a puta...