Remimazolam tosilate in upper gastrointestinal endoscopy: A multicenter, randomized, non‐inferiority, phase III trial

• Published in: Journal of gastroenterology and hepatology Vol. 36; no. 2; pp. 474 - 481
• Main Authors: Chen, Shao‐Hui, Yuan, Tang‐Mi, Zhang, Jiao, Bai, Hua, Tian, Ming, Pan, Chu‐Xiong, Bao, Hong‐Guang, Jin, Xiao‐Ju, Ji, Fu‐Hai, Zhong, Tai‐Di, Wang, Qiang, Lv, Jian‐Rui, Wang, Sheng, Li, Yu‐Juan, Yu, Yong‐Hao, Luo, Ai‐Lin, Li, Xiang‐Kui, Min, Su, Li, Lin, Zou, Xiao‐Hua, Huang, Yu‐Guang
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.02.2021
• Subjects: Adverse events; Anesthesia; benzodiazepine; endoscopic sedation; Endoscopy; GABA (A) receptor agonist; Hypotension; Propofol; remimazolam; remimazolam tosilate; Safety; Success; upper gastrointestinal endoscopy; γ-Aminobutyric acid; GABA (A) receptor agonist; remimazolam; remimazolam tosilate; endoscopic sedation; upper gastrointestinal endoscopy; benzodiazepine

Background and Aim Remimazolam tosilate (RT) is a new short‐acting GABA(A) receptor agonist, having potential to be an effective option for procedural sedation. Here, we aimed to compare the efficacy and safety of RT with propofol in patients undergoing upper gastrointestinal endoscopy. Methods This...