The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects
The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double‐blind, placebo‐controlled indep...
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Published in | Human psychopharmacology Vol. 16; no. 4; pp. 345 - 351 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Chichester, UK
John Wiley & Sons, Ltd
01.06.2001
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Subjects | |
Online Access | Get full text |
ISSN | 0885-6222 1099-1077 1099-1077 |
DOI | 10.1002/hup.306 |
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Abstract | The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double‐blind, placebo‐controlled independent group design in which subjects were randomly allocated to one of two treatment conditions, Bacopa monniera (300 mg) (n = 18) or placebo (n = 20). Neuropsychological testing was conducted before and 2 h after drug administration. No significant changes were found on any of the tests. The findings suggest that Bacopa monniera, at least for the dose administered, has no acute effects on cognitive functioning in normal healthy subjects. Copyright © 2001 John Wiley & Sons, Ltd. |
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AbstractList | The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double‐blind, placebo‐controlled independent group design in which subjects were randomly allocated to one of two treatment conditions, Bacopa monniera (300 mg) (n = 18) or placebo (n = 20). Neuropsychological testing was conducted before and 2 h after drug administration. No significant changes were found on any of the tests. The findings suggest that Bacopa monniera, at least for the dose administered, has no acute effects on cognitive functioning in normal healthy subjects. Copyright © 2001 John Wiley & Sons, Ltd. The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double‐blind, placebo‐controlled independent group design in which subjects were randomly allocated to one of two treatment conditions, Bacopa monniera (300 mg) (n = 18) or placebo (n = 20). Neuropsychological testing was conducted before and 2 h after drug administration. No significant changes were found on any of the tests. The findings suggest that Bacopa monniera , at least for the dose administered, has no acute effects on cognitive functioning in normal healthy subjects. Copyright © 2001 John Wiley & Sons, Ltd. The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double-blind, placebo-controlled independent group design in which subjects were randomly allocated to one of two treatment conditions, Bacopa monniera (300 mg) (n = 18) or placebo (n = 20). Neuropsychological testing was conducted before and 2 h after drug administration. No significant changes were found on any of the tests. The findings suggest that Bacopa monniera, at least for the dose administered, has no acute effects on cognitive functioning in normal healthy subjects. Copyright 2001 John Wiley & Sons, Ltd.The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double-blind, placebo-controlled independent group design in which subjects were randomly allocated to one of two treatment conditions, Bacopa monniera (300 mg) (n = 18) or placebo (n = 20). Neuropsychological testing was conducted before and 2 h after drug administration. No significant changes were found on any of the tests. The findings suggest that Bacopa monniera, at least for the dose administered, has no acute effects on cognitive functioning in normal healthy subjects. Copyright 2001 John Wiley & Sons, Ltd. The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of an extract of Bacopa monniera on cognitive function in normal healthy human subjects. The study was a double-blind, placebo-controlled independent group design in which subjects were randomly allocated to one of two treatment conditions, Bacopa monniera (300 mg) (n = 18) or placebo (n = 20). Neuropsychological testing was conducted before and 2 h after drug administration. No significant changes were found on any of the tests. The findings suggest that Bacopa monniera, at least for the dose administered, has no acute effects on cognitive functioning in normal healthy subjects. Copyright 2001 John Wiley & Sons, Ltd. |
Author | Lloyd, J. Stough, C. Downey, L. Hutchison, C. W. Nathan, P. J. Clarke, J. |
Author_xml | – sequence: 1 givenname: P. J. surname: Nathan fullname: Nathan, P. J. email: pnathan@bsi.swin.edu.au organization: Neuropharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Australia – sequence: 2 givenname: J. surname: Clarke fullname: Clarke, J. organization: Neuropsychology Laboratory, School of Biophysical Science and Electrical Engineering, Swinburne University of Technology, Australia – sequence: 3 givenname: J. surname: Lloyd fullname: Lloyd, J. organization: Neuropsychology Laboratory, School of Biophysical Science and Electrical Engineering, Swinburne University of Technology, Australia – sequence: 4 givenname: C. W. surname: Hutchison fullname: Hutchison, C. W. organization: Neuropsychology Laboratory, School of Biophysical Science and Electrical Engineering, Swinburne University of Technology, Australia – sequence: 5 givenname: L. surname: Downey fullname: Downey, L. organization: Neuropsychology Laboratory, School of Biophysical Science and Electrical Engineering, Swinburne University of Technology, Australia – sequence: 6 givenname: C. surname: Stough fullname: Stough, C. organization: Neuropharmacology Laboratory, Brain Sciences Institute, Swinburne University of Technology, Australia |
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Part II: The constitution of Bacoside A publication-title: Indian J Chem – ident: e_1_2_1_14_1 doi: 10.1016/0031-9422(96)00250-6 – ident: e_1_2_1_5_1 doi: 10.1007/978-1-4899-6738-1_1 – volume-title: L'examen Clinique Psychologie year: 1964 ident: e_1_2_1_27_1 – volume-title: Speed and Capacity of Language Processing Test Manual year: 1992 ident: e_1_2_1_3_1 – ident: e_1_2_1_12_1 doi: 10.2466/PMS.74.1.39-42 – ident: e_1_2_1_7_1 doi: 10.1002/(SICI)1099-1573(200005)14:3<174::AID-PTR624>3.0.CO;2-O – volume-title: Wechsler Intelligence Scale for Children year: 1991 ident: e_1_2_1_41_1 – volume-title: Neuropsychological Assessment year: 1995 ident: e_1_2_1_20_1 – ident: e_1_2_1_23_1 doi: 10.1054/mehy.2000.1099 – ident: e_1_2_1_19_1 doi: 10.1002/1097-4679(199107)47:4<548::AID-JCLP2270470413>3.0.CO;2-# – ident: e_1_2_1_2_1 – ident: e_1_2_1_13_1 doi: 10.1016/0031-9422(95)00936-1 – ident: e_1_2_1_21_1 doi: 10.1016/S0031-9422(99)00384-2 – ident: e_1_2_1_26_1 doi: 10.1016/S0031-9422(00)97026-2 – volume-title: Wechsler Memory Scale Manual year: 1974 ident: e_1_2_1_38_1 – volume: 34 start-page: 523 year: 1996 ident: e_1_2_1_37_1 article-title: Bacopa monniera Linn. as an antioxidant: mechanism of action publication-title: Indian J Exp Biol – ident: e_1_2_1_36_1 doi: 10.1121/1.1910407 – volume: 4 start-page: 89 year: 1984 ident: e_1_2_1_35_1 article-title: The psychopharmacological effects of Ginkgo biloba extract in normal healthy volunteers publication-title: J Clin Pharmacol Res – volume: 5 start-page: 84 year: 1967 ident: e_1_2_1_4_1 article-title: Chemical examination of Bacopa monniera Wettst. 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Snippet | The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of... The Ayurvedic medicine Bacopa monniera (Brahmi) has been shown to exert cognitive enhancing effects in animals. The current study examined the acute effects of... |
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Title | The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects |
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