Transzonal projections: Essential structures mediating intercellular communication in the mammalian ovarian follicle

• Published in: Molecular reproduction and development Vol. 89; no. 11; pp. 509 - 525
• Main Author: Clarke, Hugh J.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2022
• Subjects: Actin; Animals; Cell Communication; Cell interactions; Communication; Cytoskeleton; Extracellular matrix; Female; fertility; follicle; Follicles; Folliculogenesis; Germ cells; Granulosa Cells; Life cycles; Mammals; Meiosis; oocyte; Oocytes - metabolism; Ovarian Follicle; Ovulation; Somatic cells; transzonal projections; Tubulin; TZPs; Zona pellucida; oocyte; cell communication; follicle; fertility; transzonal projections; granulosa cells; TZPs

The development of germ cells relies on contact and communication with neighboring somatic cells that provide metabolic support and regulatory signals. In females, contact is achieved through thin cytoplasmic processes that project from follicle cells surrounding the oocyte, extend through an extrac...