Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress

• Published in: Journal of cellular physiology Vol. 232; no. 11; pp. 2977 - 2984
• Main Authors: Song, Shuling, Tan, Jin, Miao, Yuyang, Li, Mengmeng, Zhang, Qiang
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2017
• Subjects: Activation; Animals; Apoptosis; Apoptosis Regulatory Proteins - metabolism; Autophagy; Calcium; Caspase; Cellular stress response; Crosstalk; Endoplasmic reticulum; Endoplasmic Reticulum Stress; Homeostasis; Humans; Injury prevention; Phagocytosis; Proteins; Regulatory mechanisms (biology); Signal Transduction; Stresses; UPR; Upstream; apoptosis; autophagy; UPR; endoplasmic reticulum stress

Endoplasmic reticulum (ER) stress is a common cellular stress response that is triggered by a variety of conditions that disturb cellular homeostasis, and induces cell apoptosis. Autophagy, an important and evolutionarily conserved mechanism for maintaining cellular homeostasis, is closely related t...