MMP‐2 and MMP‐9 as prognostic markers for the early detection of urinary bladder cancer

• Published in: Journal of biochemical and molecular toxicology Vol. 33; no. 4; pp. e22275 - n/a
• Main Authors: Fouad, Hanan, Salem, Hosni, Ellakwa, Doha El‐Sayed, Abdel‐Hamid, Manal
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.04.2019
• Subjects: Bladder; Bladder cancer; Blood; Gene expression; Matrix metalloproteinase; matrix metalloproteinase‐2; matrix metalloproteinase‐9; Metalloproteinase; Proteins; Sensitivity analysis; Tissue inhibitor of metalloproteinases; Tumors; Urinary bladder; Urine; western blot analysis; matrix metalloproteinase-2; western blot analysis; matrix metalloproteinase-9; bladder cancer
• ISSN: 1095-6670; 1099-0461; 1099-0461
• DOI: 10.1002/jbt.22275

The present study assessed protein and gene expression levels of tissue inhibitor of metalloproteinase‐2 (TIMP‐2), matrix metalloproteinase‐2 (MMP‐2), and MMP‐9 in urine and blood samples of 50 patients with bladder carcinoma. The expression of TIMP‐2, MMP‐2, and MMP‐9 levels with tumor stage and gr...