Circular RNA in cardiovascular disease

• Published in: Journal of cellular physiology Vol. 234; no. 5; pp. 5588 - 5600
• Main Authors: Altesha, M‐Ashraf, Ni, Tiffany, Khan, Afaan, Liu, Kexiang, Zheng, Xiufen
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.05.2019
• Subjects: Animals; Arteriosclerosis; Atherosclerosis; biogenesis; Biomarkers; Cardiomyopathy; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - genetics; Cardiovascular Diseases - metabolism; Cardiovascular Diseases - pathology; Cardiovascular Diseases - physiopathology; Cardiovascular System - metabolism; Cardiovascular System - pathology; Cardiovascular System - physiopathology; Circular RNA; Congestive heart failure; Coronary artery; Coronary artery disease; Developmental stages; Diagnostic systems; Fibrosis; Gene expression; Gene Expression Regulation; Humans; Hypertrophy; Ischemia; miRNA sponge; Myocardial infarction; Pathogenesis; Reperfusion; Ribonucleic acid; RNA; RNA, Circular - genetics; RNA, Circular - metabolism; Senescence; Signal Transduction; Therapeutic applications; cardiovascular disease; miRNA sponge; biogenesis; circular RNA

Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and t...