Circular RNA in cardiovascular disease

Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and t...

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Published in	Journal of cellular physiology Vol. 234; no. 5; pp. 5588 - 5600
Main Authors	Altesha, M‐Ashraf, Ni, Tiffany, Khan, Afaan, Liu, Kexiang, Zheng, Xiufen
Format	Journal Article
Language	English
Published	United States Wiley Subscription Services, Inc 01.05.2019
Subjects	Animals Arteriosclerosis Atherosclerosis biogenesis Biomarkers Cardiomyopathy Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - genetics Cardiovascular Diseases - metabolism Cardiovascular Diseases - pathology Cardiovascular Diseases - physiopathology Cardiovascular System - metabolism Cardiovascular System - pathology Cardiovascular System - physiopathology Circular RNA Congestive heart failure Coronary artery Coronary artery disease Developmental stages Diagnostic systems Fibrosis Gene expression Gene Expression Regulation Humans Hypertrophy Ischemia miRNA sponge Myocardial infarction Pathogenesis Reperfusion Ribonucleic acid RNA RNA, Circular - genetics RNA, Circular - metabolism Senescence Signal Transduction Therapeutic applications cardiovascular disease miRNA sponge biogenesis circular RNA
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Abstract	Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and therapeutic interventions. Increasing evidence has implicated circRNA in the pathogenesis of multiple cardiovascular diseases. In this paper, we summarize current understanding of circRNA biogenesis, properties, expression profiles, detection methods, functions, and their implication in cardiac pathologies including/ischemia reperfusion injury, myocardial infarction, cardiac senescence, cardiac fibrosis, cardiomyopathy, cardiac hypertrophy and heart failure, atherosclerosis, coronary artery disease, and aneurysm. Increasing evidence has implicated circular RNA (circRNA) in the pathogenesis of multiple cardiovascular diseases.This review provides scientists and clinicians with a brief summary of the ever‐growing world of circRNAs and their role in cardiac diseases specifically.
AbstractList	Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and therapeutic interventions. Increasing evidence has implicated circRNA in the pathogenesis of multiple cardiovascular diseases. In this paper, we summarize current understanding of circRNA biogenesis, properties, expression profiles, detection methods, functions, and their implication in cardiac pathologies including/ischemia reperfusion injury, myocardial infarction, cardiac senescence, cardiac fibrosis, cardiomyopathy, cardiac hypertrophy and heart failure, atherosclerosis, coronary artery disease, and aneurysm. Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and therapeutic interventions. Increasing evidence has implicated circRNA in the pathogenesis of multiple cardiovascular diseases. In this paper, we summarize current understanding of circRNA biogenesis, properties, expression profiles, detection methods, functions, and their implication in cardiac pathologies including/ischemia reperfusion injury, myocardial infarction, cardiac senescence, cardiac fibrosis, cardiomyopathy, cardiac hypertrophy and heart failure, atherosclerosis, coronary artery disease, and aneurysm. Increasing evidence has implicated circular RNA (circRNA) in the pathogenesis of multiple cardiovascular diseases.This review provides scientists and clinicians with a brief summary of the ever‐growing world of circRNAs and their role in cardiac diseases specifically. Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and therapeutic interventions. Increasing evidence has implicated circRNA in the pathogenesis of multiple cardiovascular diseases. In this paper, we summarize current understanding of circRNA biogenesis, properties, expression profiles, detection methods, functions, and their implication in cardiac pathologies including/ischemia reperfusion injury, myocardial infarction, cardiac senescence, cardiac fibrosis, cardiomyopathy, cardiac hypertrophy and heart failure, atherosclerosis, coronary artery disease, and aneurysm.Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of free ends confers increased stability when compared with linear transcripts, making them ideal candidates for future diagnostic biomarkers and therapeutic interventions. Increasing evidence has implicated circRNA in the pathogenesis of multiple cardiovascular diseases. In this paper, we summarize current understanding of circRNA biogenesis, properties, expression profiles, detection methods, functions, and their implication in cardiac pathologies including/ischemia reperfusion injury, myocardial infarction, cardiac senescence, cardiac fibrosis, cardiomyopathy, cardiac hypertrophy and heart failure, atherosclerosis, coronary artery disease, and aneurysm.
Author	Altesha, M‐Ashraf Ni, Tiffany Khan, Afaan Zheng, Xiufen Liu, Kexiang
Author_xml	– sequence: 1 givenname: M‐Ashraf surname: Altesha fullname: Altesha, M‐Ashraf organization: Western University – sequence: 2 givenname: Tiffany surname: Ni fullname: Ni, Tiffany organization: Western University – sequence: 3 givenname: Afaan surname: Khan fullname: Khan, Afaan organization: University of Waterloo – sequence: 4 givenname: Kexiang surname: Liu fullname: Liu, Kexiang organization: The second Hospital of Jilin University – sequence: 5 givenname: Xiufen orcidid: 0000-0001-9988-697X surname: Zheng fullname: Zheng, Xiufen email: xzheng26@uwo.ca organization: Department of Surgery, London Health Sciences Centre
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/30341894$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1371/journal.pcbi.1005420 10.1016/0092-8674(93)90279-Y 10.1186/s12864‐017‐4386‐y 10.1080/15476286.2017.1279788 10.1111/febs.14191 10.1101/gr.202895.115 10.1261/rna.035667.112 10.1080/15476286.2016.1220473 10.1016/j.bbrc.2017.04.044 10.1161/CIRCGENETICS.117.001720 10.1002/wrna.1344 10.1016/j.yjmcc.2017.06.01509 10.1038/nsmb.2959 10.1093/nar/gkx297 10.1002/wrna.1478 10.1371/journal.pone.0151753 10.1080/10409238.2016.1276882 10.1161/CIRCRESAHA.116.309568 10.1016/j.ijcha.2017.11.001 10.1155/2017/5135781 10.1016/B978‐0‐12‐394309‐5.00006‐7 10.1038/srep34985 10.1073/pnas.73.11.3852 10.1038/srep39918 10.7150/thno.19353 10.1038/srep08057 10.1016/j.bbrc.2017.10.068 10.1093/eurheartj/ehw001 10.1007/s13238‐015‐0202‐0 10.3390/ijms15069331 10.1161/CIRCRESAHA.115.306319 10.1038/nature11993 10.1186/s12867‐015‐0034‐8 10.1016/j.molcel.2017.02.017 10.1186/s12864‐017‐4029‐3 10.1016/j.molcel.2013.08.017 10.1371/journal.pgen.1001233 10.1002/j.1460-2075.1992.tb05148.x 10.7150/thno.19764 10.1261/rna.047126.114 10.1080/15476286.2015.1022702 10.1038/nrg.2016.46 10.1016/j.celrep.2014.12.002 10.1016/j.molcel.2017.02.021 10.1016/j.molcel.2015.03.027 10.1073/pnas.92.20.9363 10.1016/j.ijcard.2015.10.051 10.7554/eLife.07540 10.1038/emboj.2011.359 10.1038/nbt.2890 10.1038/cdd.2016.133 10.1016/j.gpb.2016.02.003 10.1016/j.jacc.2016.06.040 10.1016/j.molcel.2014.08.019 10.1093/nar/28.21.4364 10.1016/j.yjmcc.2016.07.007 10.18632/oncotarget.18998 10.3892/mmr.2015.4264 10.1016/j.transproceed.2006.12.012 10.1073/pnas.93.13.6536 10.1038/nature11928 10.1093/nar/gkl1513 10.1016/0092-8674(80)90505-X 10.1161/CIRCRESAHA.117.311335 10.1016/j.jacc.2016.07.189 10.1161/ATVBAHA.111.232678 10.1016/j.ejheart.2007.11.005 10.18632/oncotarget.13656 10.1016/j.celrep.2016.03.058 10.1038/cdd.2017.61 10.1002/ejhf.801 10.1016/j.jmb.2015.02.018 10.1186/PREACCEPT‐9242556491295527 10.1038/ng.259 10.1161/CIRCGENETICS.113.000077 10.1093/eurheartj/ehv713 10.1016/j.bbrc.2013.10.151 10.1038/cr.2017.31 10.1016/0092-8674(91)90244-S 10.1093/cvr/cvw250 10.1016/j.ebiom.2017.09.015 10.1038/srep40342 10.1093/nar/gkv1458 10.1038/nature12734 10.18632/oncoscience.316 10.18632/oncotarget.19941
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References	e_1_2_13_1_72_1 e_1_2_13_1_70_1 e_1_2_13_1_30_1 e_1_2_13_1_76_1 e_1_2_13_1_32_1 e_1_2_13_1_53_1 e_1_2_13_1_74_1 e_1_2_13_1_34_1 e_1_2_13_1_55_1 e_1_2_13_1_36_1 e_1_2_13_1_57_1 e_1_2_13_1_78_1 e_1_2_13_1_38_1 e_1_2_13_1_59_1 Onwuanyi A. E. (e_1_2_13_1_51_1) 2003; 95 e_1_2_13_1_82_1 e_1_2_13_1_3_1 e_1_2_13_1_61_1 e_1_2_13_1_80_1 e_1_2_13_1_40_1 e_1_2_13_1_63_1 e_1_2_13_1_86_1 e_1_2_13_1_65_1 e_1_2_13_1_84_1 e_1_2_13_1_21_1 e_1_2_13_1_42_1 e_1_2_13_1_23_1 e_1_2_13_1_44_1 e_1_2_13_1_69_1 e_1_2_13_1_88_1 e_1_2_13_1_25_1 e_1_2_13_1_46_1 e_1_2_13_1_67_1 e_1_2_13_1_27_1 e_1_2_13_1_48_1 e_1_2_13_1_19_1 e_1_2_13_1_29_1 e_1_2_13_1_17_1 e_1_2_13_1_15_1 e_1_2_13_1_13_1 e_1_2_13_1_11_1 e_1_2_13_1_9_1 e_1_2_13_1_7_1 e_1_2_13_1_5_1 e_1_2_13_1_71_1 e_1_2_13_1_50_1 e_1_2_13_1_52_1 e_1_2_13_1_31_1 e_1_2_13_1_54_1 e_1_2_13_1_73_1 e_1_2_13_1_33_1 e_1_2_13_1_56_1 e_1_2_13_1_79_1 e_1_2_13_1_35_1 e_1_2_13_1_58_1 e_1_2_13_1_77_1 e_1_2_13_1_37_1 e_1_2_13_1_39_1 Wu T. Y. (e_1_2_13_1_75_1) 2014; 7 e_1_2_13_1_2_1 e_1_2_13_1_83_1 e_1_2_13_1_60_1 e_1_2_13_1_81_1 e_1_2_13_1_41_1 e_1_2_13_1_62_1 e_1_2_13_1_87_1 e_1_2_13_1_20_1 e_1_2_13_1_43_1 e_1_2_13_1_64_1 e_1_2_13_1_85_1 e_1_2_13_1_22_1 e_1_2_13_1_45_1 e_1_2_13_1_68_1 e_1_2_13_1_66_1 e_1_2_13_1_24_1 e_1_2_13_1_47_1 e_1_2_13_1_89_1 e_1_2_13_1_26_1 e_1_2_13_1_49_1 e_1_2_13_1_28_1 e_1_2_13_1_18_1 e_1_2_13_1_16_1 e_1_2_13_1_14_1 e_1_2_13_1_12_1 e_1_2_13_1_10_1 e_1_2_13_1_8_1 e_1_2_13_1_6_1 e_1_2_13_1_4_1
References_xml	– ident: e_1_2_13_1_80_1 doi: 10.1371/journal.pcbi.1005420 – ident: e_1_2_13_1_11_1 doi: 10.1016/0092-8674(93)90279-Y – ident: e_1_2_13_1_15_1 doi: 10.1186/s12864‐017‐4386‐y – ident: e_1_2_13_1_2_1 doi: 10.1080/15476286.2017.1279788 – ident: e_1_2_13_1_45_1 doi: 10.1111/febs.14191 – ident: e_1_2_13_1_82_1 doi: 10.1101/gr.202895.115 – ident: e_1_2_13_1_38_1 doi: 10.1261/rna.035667.112 – ident: e_1_2_13_1_57_1 doi: 10.1080/15476286.2016.1220473 – ident: e_1_2_13_1_88_1 doi: 10.1016/j.bbrc.2017.04.044 – ident: e_1_2_13_1_7_1 doi: 10.1161/CIRCGENETICS.117.001720 – ident: e_1_2_13_1_16_1 doi: 10.1002/wrna.1344 – ident: e_1_2_13_1_63_1 doi: 10.1016/j.yjmcc.2017.06.01509 – ident: e_1_2_13_1_47_1 doi: 10.1038/nsmb.2959 – ident: e_1_2_13_1_55_1 doi: 10.1093/nar/gkx297 – ident: e_1_2_13_1_74_1 doi: 10.1002/wrna.1478 – ident: e_1_2_13_1_28_1 doi: 10.1371/journal.pone.0151753 – ident: e_1_2_13_1_26_1 doi: 10.1080/10409238.2016.1276882 – ident: e_1_2_13_1_42_1 doi: 10.1161/CIRCRESAHA.116.309568 – ident: e_1_2_13_1_59_1 doi: 10.1016/j.ijcha.2017.11.001 – ident: e_1_2_13_1_23_1 doi: 10.1155/2017/5135781 – ident: e_1_2_13_1_40_1 doi: 10.1016/B978‐0‐12‐394309‐5.00006‐7 – ident: e_1_2_13_1_13_1 doi: 10.1038/srep34985 – ident: e_1_2_13_1_60_1 doi: 10.1073/pnas.73.11.3852 – ident: e_1_2_13_1_86_1 doi: 10.1038/srep39918 – ident: e_1_2_13_1_48_1 doi: 10.7150/thno.19353 – ident: e_1_2_13_1_5_1 doi: 10.1038/srep08057 – ident: e_1_2_13_1_12_1 doi: 10.1016/j.bbrc.2017.10.068 – ident: e_1_2_13_1_22_1 doi: 10.1093/eurheartj/ehw001 – ident: e_1_2_13_1_61_1 doi: 10.1007/s13238‐015‐0202‐0 – ident: e_1_2_13_1_65_1 doi: 10.3390/ijms15069331 – ident: e_1_2_13_1_8_1 doi: 10.1161/CIRCRESAHA.115.306319 – ident: e_1_2_13_1_31_1 doi: 10.1038/nature11993 – ident: e_1_2_13_1_39_1 doi: 10.1186/s12867‐015‐0034‐8 – ident: e_1_2_13_1_44_1 doi: 10.1016/j.molcel.2017.02.017 – ident: e_1_2_13_1_77_1 doi: 10.1186/s12864‐017‐4029‐3 – ident: e_1_2_13_1_85_1 doi: 10.1016/j.molcel.2013.08.017 – ident: e_1_2_13_1_9_1 doi: 10.1371/journal.pgen.1001233 – ident: e_1_2_13_1_14_1 doi: 10.1002/j.1460-2075.1992.tb05148.x – ident: e_1_2_13_1_81_1 doi: 10.7150/thno.19764 – ident: e_1_2_13_1_43_1 doi: 10.1261/rna.047126.114 – ident: e_1_2_13_1_83_1 doi: 10.1080/15476286.2015.1022702 – ident: e_1_2_13_1_62_1 doi: 10.1038/nrg.2016.46 – ident: e_1_2_13_1_64_1 doi: 10.1016/j.celrep.2014.12.002 – ident: e_1_2_13_1_52_1 doi: 10.1016/j.molcel.2017.02.021 – ident: e_1_2_13_1_58_1 doi: 10.1016/j.molcel.2015.03.027 – ident: e_1_2_13_1_20_1 doi: 10.1073/pnas.92.20.9363 – ident: e_1_2_13_1_70_1 doi: 10.1016/j.ijcard.2015.10.051 – ident: e_1_2_13_1_6_1 doi: 10.7554/eLife.07540 – ident: e_1_2_13_1_33_1 doi: 10.1038/emboj.2011.359 – ident: e_1_2_13_1_37_1 doi: 10.1038/nbt.2890 – ident: e_1_2_13_1_21_1 doi: 10.1038/cdd.2016.133 – ident: e_1_2_13_1_36_1 doi: 10.1016/j.gpb.2016.02.003 – ident: e_1_2_13_1_69_1 doi: 10.1016/j.jacc.2016.06.040 – ident: e_1_2_13_1_4_1 doi: 10.1016/j.molcel.2014.08.019 – ident: e_1_2_13_1_10_1 doi: 10.1093/nar/28.21.4364 – ident: e_1_2_13_1_73_1 doi: 10.1016/j.yjmcc.2016.07.007 – ident: e_1_2_13_1_89_1 doi: 10.18632/oncotarget.18998 – volume: 7 start-page: 56 year: 2014 ident: e_1_2_13_1_75_1 article-title: MiR‐19a is correlated with prognosis and apoptosis of laryngeal squamous cell carcinoma by regulating TIMP‐2 expression publication-title: International Journal of Clinical and Experimental Pathology – ident: e_1_2_13_1_87_1 doi: 10.3892/mmr.2015.4264 – ident: e_1_2_13_1_29_1 doi: 10.1016/j.transproceed.2006.12.012 – ident: e_1_2_13_1_79_1 doi: 10.1073/pnas.93.13.6536 – volume: 95 start-page: 1146 year: 2003 ident: e_1_2_13_1_51_1 article-title: Cardiovascular disease mortality publication-title: Journal of the National Medical Association – ident: e_1_2_13_1_49_1 doi: 10.1038/nature11928 – ident: e_1_2_13_1_66_1 doi: 10.1093/nar/gkl1513 – ident: e_1_2_13_1_3_1 doi: 10.1016/0092-8674(80)90505-X – ident: e_1_2_13_1_30_1 doi: 10.1161/CIRCRESAHA.117.311335 – ident: e_1_2_13_1_17_1 doi: 10.1016/j.jacc.2016.07.189 – ident: e_1_2_13_1_35_1 doi: 10.1161/ATVBAHA.111.232678 – ident: e_1_2_13_1_27_1 doi: 10.1016/j.ejheart.2007.11.005 – ident: e_1_2_13_1_56_1 doi: 10.18632/oncotarget.13656 – ident: e_1_2_13_1_84_1 doi: 10.1016/j.celrep.2016.03.058 – ident: e_1_2_13_1_71_1 doi: 10.1038/cdd.2017.61 – ident: e_1_2_13_1_18_1 doi: 10.1002/ejhf.801 – ident: e_1_2_13_1_41_1 doi: 10.1016/j.jmb.2015.02.018 – ident: e_1_2_13_1_24_1 doi: 10.1186/PREACCEPT‐9242556491295527 – ident: e_1_2_13_1_53_1 doi: 10.1038/ng.259 – ident: e_1_2_13_1_19_1 doi: 10.1161/CIRCGENETICS.113.000077 – ident: e_1_2_13_1_72_1 doi: 10.1093/eurheartj/ehv713 – ident: e_1_2_13_1_34_1 doi: 10.1016/j.bbrc.2013.10.151 – ident: e_1_2_13_1_78_1 doi: 10.1038/cr.2017.31 – ident: e_1_2_13_1_50_1 doi: 10.1016/0092-8674(91)90244-S – ident: e_1_2_13_1_67_1 doi: 10.1093/cvr/cvw250 – ident: e_1_2_13_1_46_1 doi: 10.1016/j.ebiom.2017.09.015 – ident: e_1_2_13_1_68_1 doi: 10.1038/srep40342 – ident: e_1_2_13_1_32_1 doi: 10.1093/nar/gkv1458 – ident: e_1_2_13_1_25_1 doi: 10.1038/nature12734 – ident: e_1_2_13_1_76_1 doi: 10.18632/oncoscience.316 – ident: e_1_2_13_1_54_1 doi: 10.18632/oncotarget.19941
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Snippet	Circular RNA (circRNA) are endogenous transcripts that display differential expression across species, developmental stages, and pathologies. Their lack of...
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SubjectTerms	Animals Arteriosclerosis Atherosclerosis biogenesis Biomarkers Cardiomyopathy Cardiovascular disease Cardiovascular diseases Cardiovascular Diseases - genetics Cardiovascular Diseases - metabolism Cardiovascular Diseases - pathology Cardiovascular Diseases - physiopathology Cardiovascular System - metabolism Cardiovascular System - pathology Cardiovascular System - physiopathology Circular RNA Congestive heart failure Coronary artery Coronary artery disease Developmental stages Diagnostic systems Fibrosis Gene expression Gene Expression Regulation Humans Hypertrophy Ischemia miRNA sponge Myocardial infarction Pathogenesis Reperfusion Ribonucleic acid RNA RNA, Circular - genetics RNA, Circular - metabolism Senescence Signal Transduction Therapeutic applications
Title	Circular RNA in cardiovascular disease
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