Cell therapy for ischemic stroke: Are differences in preclinical and clinical study design responsible for the translational loss of efficacy?

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Published inAnnals of neurology Vol. 86; no. 1; pp. 5 - 16
Main Authors Cui, Li‐li, Golubczyk, Dominika, Tolppanen, Anna‐Maija, Boltze, Johannes, Jolkkonen, Jukka
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.07.2019
Wiley Subscription Services, Inc
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Author Jolkkonen, Jukka
Cui, Li‐li
Golubczyk, Dominika
Boltze, Johannes
Tolppanen, Anna‐Maija
Author_xml – sequence: 1
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  surname: Cui
  fullname: Cui, Li‐li
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  givenname: Dominika
  surname: Golubczyk
  fullname: Golubczyk, Dominika
  organization: School of Medicine, Collegium Medicum, University of Warmia and Mazury
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  givenname: Anna‐Maija
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  fullname: Tolppanen, Anna‐Maija
  organization: University of Eastern Finland
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  givenname: Johannes
  surname: Boltze
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  organization: University of Warwick
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  givenname: Jukka
  surname: Jolkkonen
  fullname: Jolkkonen, Jukka
  email: jukka.jolkkonen@uef.fi
  organization: Neurocenter, Kuopio University Hospital
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SubjectTerms Animals
Brain Ischemia - diagnosis
Brain Ischemia - therapy
Cell- and Tissue-Based Therapy - methods
Cell- and Tissue-Based Therapy - trends
Clinical Trials as Topic - methods
Disease Models, Animal
Humans
Ischemia
Stroke
Stroke - diagnosis
Stroke - therapy
Translational Medical Research - methods
Translational Medical Research - trends
Treatment Outcome
Title Cell therapy for ischemic stroke: Are differences in preclinical and clinical study design responsible for the translational loss of efficacy?
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fana.25493
https://www.ncbi.nlm.nih.gov/pubmed/31020699
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Volume 86
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