Electrical stimulation of microengineered skeletal muscle tissue: Effect of stimulus parameters on myotube contractility and maturation

• Published in: Journal of tissue engineering and regenerative medicine Vol. 12; no. 4; p. 912
• Main Authors: Banan Sadeghian, Ramin, Ebrahimi, Majid, Salehi, Sahar
• Format: Journal Article
• Language: English
• Published: England 01.04.2018
• Subjects: skeletal muscle tissue engineering; electrical stimulation; micropatterning; myogenesis; myotube contractility; myotube maturation

Skeletal muscle tissues engineered in vitro are aneural, are short in the number of fibres required to function properly and degenerate rapidly. Electrical stimulation has been widely used to compensate for such a lack of neural activity, yet the relationship between the stimulation parameters and t...