N-Acetylcysteine suppresses TNF-induced NF-κB activation through inhibition of IκB kinases - Oka, Shin-ichi; Kamata, Hideaki; Kamata, Keiko; Yagisawa, Hitoshi; Hirata, Hajime (FEBS letters, 2000)
Keywords: BSO, L-buthionine-(S,R)-sulfoximine; DTNB, 5-dithiobis(2-nitrobenzoic acid); DTT, dithiothreitol; GSH, glutathione; IKK, IκB kinase; IκB kinase; N-Acetyl-L-cysteine; NAA, N-acetylalanine; NAC, N-acetyl-L-cysteine; NF-κB, nuclear factor κB; NIK, NF-κB-inducing kinase; Nuclear factor κB; Redox; ROS, reactive oxygen species; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis; TNF, tumor necrosis factor; TRADD, TNF receptor-associated death domain protein; TRAF2, TNF receptor-associated factor 2; Tumor necrosis factor; NAC, N-acetyl-L-cysteine; GSH, glutathione; IKK, IκB kinase; TNF, tumor necrosis factor; BSO, L-buthionine-(S,R)-sulfoximine; DTNB, 5-dithiobis(2-nitrobenzoic acid); NAA, N-acetylalanine; NF-κB, nuclear factor κB; Redox; IκB kinase; DTT, dithiothreitol; TRAF2, TNF receptor-associated factor 2; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis; Tumor necrosis factor; TRADD, TNF receptor-associated death domain protein; N-Acetyl-L-cysteine; ROS, reactive oxygen species; NIK, NF-κB-inducing kinase; Nuclear factor κB