Nuclear sorting of RNA

• Published in: Wiley interdisciplinary reviews. RNA Vol. 11; no. 2; p. e1572
• Main Authors: Garland, William, Jensen, Torben Heick
• Format: Journal Article
• Language: English
• Published: United States 01.03.2020
• Subjects: RNA decay; RNA sorting; RNA retention; RNA exosome complex

The majority of the mammalian genome is transcribed by RNA polymerase II, yielding a vast amount of noncoding RNA (ncRNA) in addition to the standard production of mRNA. The typical nuclear biogenesis of mRNA relies on the tightly controlled coupling of co- and post-transcriptional processing events...