MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer

• Published in: Journal of cellular physiology Vol. 233; no. 2; pp. 901 - 913
• Main Authors: Moridikia, Abdullah, Mirzaei, Hamed, Sahebkar, Amirhossein, Salimian, Jafar
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2018
• Subjects: Abnormalities; Animals; Biomarkers; Biomarkers, Tumor - genetics; Cancer; Chromosome aberrations; Colon; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - genetics; Colorectal Neoplasms - mortality; Colorectal Neoplasms - therapy; Deregulation; Diagnosis; Diagnostic software; Diagnostic systems; Environmental risk; Gene Expression Regulation, Neoplastic; Genetics; Humans; Medical prognosis; microRNA; MicroRNAs; MicroRNAs - genetics; miRNA; Molecular Diagnostic Techniques; Pathogenesis; Patients; Population genetics; Predictive Value of Tests; Prognosis; Proteins; Public health; Risk analysis; Risk factors; Signal Transduction; Target detection; therapy; diagnosis; microRNA; colorectal cancer; therapy

Colorectal cancer (CRC) is known as the third common cancer worldwide and an important public health problem in different populations. Several genetics and environmental risk factors are involved in the development and progression of CRC including chromosomal abnormalities, epigenetic alterations, a...