Solvent detergent treated pooled plasma and reduction of allergic transfusion reactions

• Published in: Transfusion (Philadelphia, Pa.) Vol. 60; no. 1; pp. 54 - 61
• Main Authors: McGonigle, Andrea M., Patel, Eshan U., Waters, Kevin M., Moliterno, Alison R., Thoman, Sandra K., Vozniak, Sonja O., Ness, Paul M., King, Karen E., Tobian, Aaron A. R., Lokhandwala, Parvez M.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.01.2020; Wiley Subscription Services, Inc
• Subjects: Hypersensitivity; Plasma; Risk analysis; Risk factors; Risk reduction; Solvents; Thrombocytopenic purpura; Thrombotic thrombocytopenic purpura; Transfusion

BACKGROUND Thrombotic thrombocytopenic purpura (TTP) patients have increased risk for allergic transfusion reactions (ATR) due to the number of plasma products they require. This study evaluated the efficacy of solvent detergent treated plasma (S/D treated plasma) to reduce ATRs. STUDY DESIGN AND ME...