Cancer stem cells (CSCs) in cancer progression and therapy - Najafi, Masoud; Farhood, Bagher; Mortezaee, Keywan (Journal of cellular physiology, 2019)
Keywords: Antigens; Antineoplastic Agents - therapeutic use; Biomarkers; Cancer; cancer cell; cancer stem cell (CSC); Cancer-Associated Fibroblasts - drug effects; Cancer-Associated Fibroblasts - pathology; cancer‐associated fibroblast (CAF); CD133; CD44; Cell Differentiation - genetics; Cell self-renewal; Cell surface; Cells (biology); CSC niche; dedifferentiation; Differentiation; Epithelial-Mesenchymal Transition - genetics; epithelial–mesenchymal transition (EMT); Fibroblasts; Growth factors; Humans; Hypoxia; Immunotherapy; Metastases; Neoplasms - drug therapy; Neoplasms - genetics; Neoplasms - pathology; Neoplastic Stem Cells - pathology; Notch; Phenotypes; Progenitor cells; Signal Transduction - drug effects; siRNA; Stem Cell Niche - genetics; Stem cells; Surface markers; Therapy; therapy resistance; Transforming growth factor; Transforming growth factor-b; transforming growth factor‐β (TGF‐β); Tumor Hypoxia - drug effects; tumor microenvironment (TME); Tumor Microenvironment - drug effects; Tumor Microenvironment - genetics; Tumors; WNT; Wnt protein; β‐catenin; hypoxia; tumor microenvironment (TME); transforming growth factor-β (TGF-β); Notch; cancer-associated fibroblast (CAF); dedifferentiation; cancer stem cell (CSC); therapy resistance; epithelial-mesenchymal transition (EMT); β-catenin; cancer cell; WNT; CD44; CSC niche; CD133