Digital laser doppler flowmetry may discriminate “limited” from “diffuse” systemic sclerosis

• Published in: Microvascular research Vol. 80; no. 2; pp. 221 - 226
• Main Authors: Grattagliano, Vito, Iannone, Florenzo, Praino, Emanuela, De Zio, Alessandra, Riccardi, Maria Teresa, Carrozzo, Norma, Covelli, Michele, Maggi, Paolo, Lapadula, Giovanni
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2010
• Subjects: Adult; Blood Flow Velocity; Capillaries - diagnostic imaging; Capillaries - pathology; Capillaries - physiopathology; Cold test; Diagnosis, Differential; Endothelium; Female; Humans; Ischemic test; Laser-Doppler Flowmetry - methods; Male; Microcirculation; Middle Aged; Nails - blood supply; Raynaud; Raynaud Disease - diagnostic imaging; Raynaud Disease - pathology; Regional Blood Flow; Scleroderma, Diffuse - diagnostic imaging; Scleroderma, Diffuse - pathology; Scleroderma, Diffuse - physiopathology; Scleroderma, Limited - diagnostic imaging; Scleroderma, Limited - pathology; Scleroderma, Limited - physiopathology; Skin - blood supply; Skin - pathology; Ultrasonography; Vascular tone; Videocapillaroscopy; Videocapillaroscopy; Ischemic test; Cold test; Vascular tone; Raynaud; Endothelium

To investigate skin blood flux and microvascular functional changes by laser Doppler flowmetry (LD) in patients with systemic sclerosis (SSc) at baseline and following dynamic stimulations. Skin blood flux of the dorsal hands was recorded by LD at baseline and after the cold test and the post-occlus...