Glycosylation in viral hepatitis

• Published in: Biochimica et biophysica acta. General subjects Vol. 1865; no. 11; p. 129997
• Main Authors: Gruszewska, Ewa, Grytczuk, Agnieszka, Chrostek, Lech
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.11.2021
• Subjects: biomarkers; biosynthesis; blood serum; chronic hepatitis; fibrosis; Glycoproteins; Glycosylation; humans; liver; N-glycome; polysaccharides; Viral hepatitis; viruses; Viral hepatitis; Glycosylation; Glycoproteins; N-glycome

The interaction between hepatitis viruses and host cells is regulated by glycans exposed on the surfaces of human and viruses cells. As the biosynthesis and degradation of human glycoproteins take place at the highest level in the liver, the changes in glycosylation of serum proteins may potentially...