Physiological functions and pharmacological and toxicological effects of p-octopamine

• Published in: Drug and chemical toxicology (New York, N.Y. 1978) Vol. 38; no. 1; pp. 106 - 112
• Main Author: Stohs, Sidney J.
• Format: Journal Article
• Language: English
• Published: United States Informa Healthcare USA, Inc 01.01.2015; Informa Healthcare
• Subjects: Adrenergic receptors; Animals; biomarker; Body Weight - drug effects; Humans; Hypotension - drug therapy; metabolism; Molecular Structure; norsynephrine; Octopamine - isolation & purification; Octopamine - pharmacology; Octopamine - physiology; Octopamine - toxicity; prohibited substance; Protein Binding - physiology; Receptors, Biogenic Amine - metabolism; Stereoisomerism; trace amines; weight loss; norsynephrine; prohibited substance; weight loss; Adrenergic receptors; metabolism; biomarker; trace amines

Abstract p-Octopamine occurs naturally in plants, invertebrates and animals with diverse functions and effects. This review summarizes the chemistry, metabolism, receptor binding characteristics, known physiological functions, and pharmacological and toxicological effects of p-octopamine. Databases...