Radiation-induced changes in DNA methylation and their relationship to chromosome aberrations in nuclear power plant workers

• Published in: International journal of radiation biology Vol. 91; no. 2; pp. 142 - 149
• Main Authors: Lee, Younghyun, Kim, Yang Jee, Choi, Young Joo, Lee, Joong Won, Lee, Sunyeong, Cho, Yoon Hee, Chung, Hai Won
• Format: Journal Article
• Language: English
• Published: England Informa Healthcare 01.02.2015; Taylor & Francis
• Subjects: Adult; Aged; Case-Control Studies; chromosome aberrations; Chromosome Aberrations - radiation effects; DNA methylation; DNA Methylation - radiation effects; Humans; Male; Middle Aged; nuclear power plant workers; Nuclear Power Plants; Occupational Exposure - adverse effects; Radiation; Repetitive Sequences, Nucleic Acid - genetics; nuclear power plant workers; DNA methylation; chromosome aberrations; Radiation

Abstract Purpose: We investigated the association between occupational radiation exposure and DNA methylation changes in nuclear power plant workers. We also evaluated whether radiation- induced DNA methylation alterations are associated with chromosome aberrations. Materials and methods: The study...