Total Synthesis of Marine Cyclic Enol-Phosphotriester Salinipostin Compounds

• Published in: Journal of Ocean University of China Vol. 17; no. 3; pp. 683 - 689
• Main Authors: Zhao, Mingliang, Wei, Xianfeng, Liu, Xuemeng, Dong, Xueyang, Yu, Rilei, Wan, Shengbiao, Jiang, Tao
• Format: Journal Article
• Language: English
• Published: Heidelberg Science Press 01.06.2018; Springer Nature B.V; Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy,Ocean University of China, Qingdao 266003, China%Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy,Ocean University of China, Qingdao 266003, China; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology,Qingdao 266003, China
• Subjects: Antiinfectives and antibacterials; Aromatic compounds; Aromatic hydrocarbons; Biodiversity; Biological activity; Carbon 13; Central nervous system; Chemical compounds; Chemical synthesis; Combinatorial analysis; Combinatorial libraries; Deoxyribonucleic acid; Dihydroxyacetone; DNA; Drug discovery; Drugs; Earth and Environmental Science; Earth Sciences; Embedded systems; Fermentation; Frameworks; Lead; Marine biology; Mass spectrometry; Mass spectroscopy; Meteorology; Natural products; Neoplasms; NMR; Nuclear magnetic resonance; Oceanography; Parasites; Pharmacology; Phospholipids; Polycyclic aromatic hydrocarbons; Viruses; enolphosphate trimester; total synthesis; Salinipostin

Due to their structural diversity and variety of biological activities, marine natural products have been the subject of extensive study. These compounds, especially phospholipid polycyclic aromatic hydrocarbons, have a wide range of pharmacological applications, including embedded DNA and central n...