Role of surrogate markers in assessing patients with diabetes mellitus and the metabolic syndrome and in evaluating lipid-lowering therapy

• Published in: The American journal of cardiology Vol. 93; no. 11; pp. 32 - 48
• Main Authors: Rajaram, Venkataraman, Pandhya, Sanjay, Patel, Samir, Meyer, Peter M, Goldin, Marshall, Feinstein, Matt J.M, Neems, Rachel, Liebson, Philip R, Fiedler, Benjamin M, Macioch, James E, Feinstein, Steven B
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 03.06.2004; Elsevier; Elsevier Limited
• Subjects: Adult; Aged; Biological and medical sciences; Biomarkers - analysis; Biopsy, Needle; Blood Glucose - analysis; Cardiology. Vascular system; Cardiovascular Diseases - prevention & control; Carotid Stenosis - diagnosis; Carotid Stenosis - prevention & control; Comorbidity; Coronary Angiography - methods; Coronary Artery Disease - diagnosis; Coronary Artery Disease - prevention & control; Diabetes; Diabetes Mellitus - diagnosis; Diabetes Mellitus - drug therapy; Diabetes Mellitus - epidemiology; Female; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Immunohistochemistry; Lipids; Male; Medical imaging; Medical sciences; Medical screening; Medical treatment; Metabolic diseases; Metabolic Syndrome - diagnosis; Metabolic Syndrome - drug therapy; Metabolic Syndrome - epidemiology; Metabolism; Middle Aged; Miscellaneous; Mortality; Other metabolic disorders; Prognosis; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Severity of Illness Index; Tunica Intima - drug effects; Tunica Intima - pathology; Ultrasonography, Doppler; United States; US; Endocrinopathy; Human; Treatment; X Syndrome; Diabetes mellitus; Biological marker; Cardiovascular disease; Metabolic diseases; Lipids; Circulatory system; Cardiology; Phlebology

Diabetes mellitus and the metabolic syndrome (MS) are reaching epidemic proportions in the United States, and cardiovascular disease continues to be the leading cause of death among patients with diabetes. A range of noninvasive screening tools may help reduce the morbidity and mortality of patients...