Human brain networks in cognitive decline: a graph theoretical analysis of cortical connectivity from EEG data

• Published in: Journal of Alzheimer's disease Vol. 41; no. 1; p. 113
• Main Authors: Vecchio, Fabrizio, Miraglia, Francesca, Marra, Camillo, Quaranta, Davide, Vita, Maria Gabriella, Bramanti, Placido, Rossini, Paolo Maria
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2014
• Subjects: Aged; Alpha Rhythm - physiology; Alzheimer Disease - physiopathology; Brain - physiopathology; Brain Mapping - methods; Cerebral Cortex - physiopathology; Cognitive Dysfunction - physiopathology; Delta Rhythm - physiology; Electroencephalography - methods; Female; Humans; Male; Neural Pathways - physiopathology; Signal Processing, Computer-Assisted; Software; Theta Rhythm - physiology; delta and alpha bands; functional connectivity; graph theory; EEG; sLORETA/eLORETA; mild cognitive impairment; Alzheimer's disease

The aim of this study was to investigate the neuronal network characteristics in physiological and pathological brain aging. A database of 378 participants divided in three groups was analyzed: Alzheimer's disease (AD), mild cognitive impairment (MCI), and normal elderly (Nold) subjects. Throug...