Age-related analysis of structural, biochemical and mechanical properties of the porcine mitral heart valve leaflets

• Published in: Connective tissue research Vol. 54; no. 6; pp. 394 - 402
• Main Authors: Kasyanov, Vladimir, Moreno-Rodriguez, Ricardo A., Kalejs, Martins, Ozolanta, Iveta, Stradins, Peteris, Wen, Xuejun, Yao, Hai, Mironov, Vladimir
• Format: Journal Article
• Language: English
• Published: England Informa Healthcare USA, Inc 01.01.2013; Taylor & Francis
• Subjects: Aging - physiology; Animals; Biomechanical Phenomena; Biomechanics; collagen; Collagen - metabolism; Cross-Linking Reagents - metabolism; Fetus - anatomy & histology; Fetus - physiology; heart valve; Mitral Valve - anatomy & histology; Mitral Valve - embryology; Mitral Valve - physiology; Mitral Valve - ultrastructure; porcine; stress-strain; Sus scrofa

Abstract The aim of this study was to assess structural and biochemical differences in the extracellular matrix of the fetal and adult porcine mitral heart valves in relation to their mechanical characteristics. Using tensile tests it was demonstrated that the material properties of porcine mitral h...