Abnormal expression of circRNA_089763 in the plasma exosomes of patients with post‑operative cognitive dysfunction after coronary artery bypass grafting

• Published in: Molecular medicine reports Vol. 20; no. 3; pp. 2549 - 2562
• Main Authors: Wang, Maozhou, Su, Pixiong, Liu, Yan, Zhang, Xitao, Yan, Jun, An, Xiangguang, Wang, Xiaobin, Gu, Song
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications UK Ltd 01.09.2019; D.A. Spandidos
• Subjects: Adult; Age; Aged; Aged, 80 and over; Anxiety; Bioinformatics; Biomarkers; Body mass index; Bypass; Cancer; Central nervous system; Cognitive ability; Cognitive Dysfunction - blood; Cognitive Dysfunction - etiology; Computational Biology - methods; Coronary artery; Coronary Artery Bypass - adverse effects; Coronary vessels; Disease; DNA microarrays; Exosomes; Exosomes - metabolism; Exosomes - ultrastructure; Female; Gene Expression; Gene Expression Profiling; Gene Ontology; Genomes; Heart surgery; Hospitals; Humans; Male; Memory; Mental disorders; Middle Aged; miRNA; Non-coding RNA; Peripheral blood; Plasma; Postoperative Period; Quality of life; Reverse transcription; RNA, Circular - blood; Beijing China; New York; United States > US; China

Post‑operative cognitive dysfunction (POCD) is a complication of the central nervous system characterized by mental disorders, anxiety, personality changes and impaired memory. POCD occurs frequently after coronary artery bypass grafting (CABG) and can severely affect quality of life for patients. T...