Investigation of the apoptotic effect of curcumin in human leukemia HL-60 cells by using flow cytometry

• Published in: Cancer biotherapy & radiopharmaceuticals Vol. 25; no. 6; pp. 749 - 755
• Main Authors: Dikmen, Miriş, Canturk, Zerrin, Ozturk, Yusuf, Tunali, Yagmur
• Format: Journal Article
• Language: English
• Published: United States Mary Ann Liebert, Inc 01.12.2010
• Subjects: Apoptosis; Apoptosis - drug effects; Caspase 3 - metabolism; Cell Survival - drug effects; Chemical properties; Curcuma longa; Curcumin - pharmacology; Development and progression; Dose-Response Relationship, Drug; Flow Cytometry; Health aspects; HL-60 Cells; Humans; Leukemia; Leukemia - drug therapy; Methods; Observations; Turmeric; Turkey

Curcumin (diferuloylmethane), the major yellow pigment isolated from the turmeric (Curcuma longa), has received much attention due to several biological properties. Curcumin exhibits a variety of pharmacological effects including antitumor, anti-inflammatory, and anti-infectious activities. In the p...