HLA inherence as a potential parameter in checkpoint inhibitor-associated autoimmune adverse event assessment

• Published in: Frontiers in medicine Vol. 10; p. 1288844
• Main Authors: Gandarillas, Sophia, Newland, Elizabeth Schoenberg, Toppmeyer, Deborah, Stephenson, Ryan, Denzin, Lisa, Dasgeb, Bahar
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 08.01.2024
• Subjects: checkpoint inhibitors; HLA; HLA inherence; irAE; Medicine; oncology; HLA inherence; HLA; irAE; checkpoint inhibitors; oncology

The success of immunotherapy has made it a lifesaving treatment, but not without side effects. Currently, the risk factors for developing immune-related adverse events (irAEs) in patients who receive immunotherapy are poorly understood, and there is no risk-stratifying mechanism for potentially fata...