A fluorometric skin-interfaced microfluidic device and smartphone imaging module for in situ quantitative analysis of sweat chemistry

• Published in: Lab on a chip Vol. 18; no. 15; pp. 2178 - 2186
• Main Authors: Sekine, Yurina, Kim, Sung Bong, Zhang, Yi, Bandodkar, Amay J., Xu, Shuai, Choi, Jungil, Irie, Masahiro, Ray, Tyler R., Kohli, Punit, Kozai, Naofumi, Sugita, Tsuyoshi, Wu, Yixin, Lee, KunHyuck, Lee, Kyu-Tae, Ghaffari, Roozbeh, Rogers, John A.
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 01.01.2018
• Subjects: Biomarkers; Chemical sensors; Chlorides - analysis; Collection; Colorimetry; Electrical measurement; Excretion; Fluorescent indicators; Fluorometry - instrumentation; Human performance; Humans; Imaging; In situ measurement; Lab-On-A-Chip Devices; Metabolites; Microchannels; Microfluidic devices; Microfluidics; Molecular Imaging - instrumentation; Organic chemistry; Quantitative analysis; Skin; Skin - chemistry; Smartphone; Smartphones; Sodium - analysis; Sweat; Sweat - chemistry; Zinc - analysis

The rich composition of solutes and metabolites in sweat and its relative ease of collection upon excretion from skin pores make this class of biofluid an attractive candidate for point of care analysis. Wearable technologies that combine electrochemical sensors with conventional or emerging semicon...