Bone hyperalgesia after mechanical impact stimulation: A human experimental pain model

• Published in: Somatosensory & motor research Vol. 31; no. 4; pp. 178 - 185
• Main Authors: Finocchietti, Sara, Graven-Nielsen, Thomas, Arendt-Nielsen, Lars
• Format: Journal Article
• Language: English
• Published: England Informa UK Ltd 01.12.2014; Taylor & Francis
• Subjects: Adult; Analysis of Variance; Biophysics; Bone and Bones - physiopathology; Bone pain; experimental pain; Female; Humans; hyperalgesia; Hyperalgesia - pathology; Hyperalgesia - physiopathology; Male; Pain Measurement; Pain Threshold - physiology; Physical Stimulation - adverse effects; Pressure - adverse effects; quantitative sensory testing; temporal summation; Young Adult; hyperalgesia; temporal summation; experimental pain; quantitative sensory testing; Bone pain

Abstract Hyperalgesia in different musculoskeletal structures including bones is a major clinical problem. An experimental bone hyperalgesia model was developed in the present study. Hyperalgesia was induced by three different weights impacted on the shinbone in 16 healthy male and female subjects....