Understanding and Overcoming the Challenges Related to Cardiovascular Trials Involving Patients with Kidney Disease

• Published in: Clinical journal of the American Society of Nephrology Vol. 16; no. 9; pp. 1435 - 1444
• Main Authors: Ishida, Julie H, Chauhan, Cynthia, Gillespie, Barbara, Gruchalla, Ken, McCullough, Peter A, Quella, Susan, Romero, Alain, Rossignol, Patrick, Wheeler, David C, Malley, Meaghan A, West, Melissa, Herzog, Charles A
• Format: Journal Article
• Language: English
• Published: United States American Society of Nephrology 01.09.2021
• Subjects: Cardiology and cardiovascular system; Cardiovascular Diseases - complications; Clinical Trials as Topic - standards; Human health and pathology; Humans; Kidney Diseases - complications; Life Sciences; Patient Selection; Research Design; kidney disease; cardiorenal; cardiovascular; cardiovascular trials

Cardiovascular disease is a prevalent and prognostically important comorbidity among patients with kidney disease, and individuals with kidney disease make up a sizeable proportion (30%-60%) of patients with cardiovascular disease. However, several systematic reviews of cardiovascular trials have ob...