Association of IL23R and ATG16L1 with susceptibility of Crohn's disease in Chinese population

• Published in: Scandinavian journal of gastroenterology Vol. 49; no. 10; p. 1201
• Main Authors: Zhang, Jie, Chen, Jiebin, Gu, Jianjun, Guo, Huimin, Chen, Weichang
• Format: Journal Article
• Language: English
• Published: England 01.10.2014
• Subjects: Adult; Asian Continental Ancestry Group - genetics; Autophagy-Related Proteins; Carrier Proteins - genetics; Case-Control Studies; China - ethnology; Crohn Disease - genetics; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Nod2 Signaling Adaptor Protein - genetics; Polymorphism, Single Nucleotide; Receptors, Interleukin - genetics; Chinese population; gene polymorphism; ATG16L1; IL23R; Crohn’s disease

To investigate whether gene polymorphisms of ATG16L1 and IL23R are associated with the susceptibility of Crohn's disease (CD) in Chinese population. A total of 420 patients with CD and 450 age- and sex-matched healthy volunteers from Chinese Han population were included in this study. Single nu...