Linker-modified quinoline derivatives targeting HIV-1 integrase: synthesis and biological activity
A series of quinoline derivatives linked to an aromatic ring by functionalized spacers was synthesized. The anti-HIV-1 integrase potency was evaluated in both in vitro and ex vivo assays. A novel series of HIV-1 integrase inhibitors was synthesized and tested in both in vitro and ex vivo assays. The...
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Published in | Bioorganic & medicinal chemistry letters Vol. 14; no. 10; pp. 2473 - 2476 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford
Elsevier Ltd
17.05.2004
Elsevier |
Subjects | |
Online Access | Get full text |
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