Increased risk of vascular complications in Takayasu's arteritis patients with positive lupus anticoagulant

• Published in: Scandinavian journal of rheumatology Vol. 44; no. 3; pp. 211 - 214
• Main Authors: Jordan, NP, Bezanahary, H, D'Cruz, DP
• Format: Journal Article
• Language: English
• Published: England Informa Healthcare 01.05.2015
• Subjects: Adult; Antibodies, Anticardiolipin - immunology; Anticoagulants - therapeutic use; Antiphospholipid Syndrome - complications; Aortic Valve - surgery; Bicuspid Aortic Valve Disease; Carotid Artery Diseases - etiology; Coronary Artery Disease - etiology; Enzyme-Linked Immunosorbent Assay; Female; Femoral Artery; Heart Defects, Congenital - etiology; Heart Defects, Congenital - surgery; Heart Valve Diseases - etiology; Heart Valve Diseases - surgery; Heart Valve Prosthesis Implantation; Humans; Immunoglobulin G - immunology; Immunoglobulin M - immunology; Immunosuppressive Agents - therapeutic use; Ischemic Attack, Transient - etiology; Kidney Failure, Chronic - etiology; Lupus Coagulation Inhibitor - immunology; Male; Middle Aged; Peripheral Arterial Disease - etiology; Renal Artery; Retrospective Studies; Risk Factors; Stroke - etiology; Takayasu Arteritis - complications; Takayasu Arteritis - drug therapy; Takayasu Arteritis - immunology; Vision Disorders - etiology; Young Adult

Objectives: Previous studies have shown antiphospholipid antibodies (aPL) to be prevalent in primary systemic vasculitides; however, the possible clinical impact of aPL positivity in such patients has not been explored in depth. The aims of this study were to determine the prevalence of aPL in patie...