Cigarette smoke extract stimulates PCSK9 production in HepG2 cells via ROS/NF‑κB signaling - Ma, Baitao; Wang, Xuebin; Zhang, Rui; Niu, Shuai; Rong, Zhihua; Ni, Leng; Di, Xiao; Han, Qin; Liu, Changwei (Molecular medicine reports, 2021)
Keywords: Animals; Arteriosclerosis; Atherosclerosis; Atherosclerosis - chemically induced; Atherosclerosis - genetics; Atherosclerosis - pathology; Biotechnology; Cardiovascular disease; Cholesterol; Cigarette smoke; Cigarette Smoking - adverse effects; Cigarettes; Dyslipidemia; Experiments; Fluorides; Gene expression; Gene Expression Regulation - drug effects; Hep G2 Cells; Hepatocytes; Humans; Kexin; Low density lipoprotein receptors; Melatonin; NF-kappa B - genetics; NF-κB protein; Polymerase chain reaction; Proprotein Convertase 9 - genetics; Proprotein convertases; Protein-Tyrosine Kinases - genetics; Proteins; Proto-Oncogene Proteins - genetics; Reactive Oxygen Species; Receptor density; Receptors, LDL - genetics; Reverse transcription; Risk factors; Signal Transduction - drug effects; Smoking - adverse effects; Software; Subtilisin; Tumor necrosis factor-TNF; Western blotting