Variance estimation for clustered recurrent event data with a small number of clusters

• Published in: Statistics in medicine Vol. 24; no. 19; pp. 3037 - 3051
• Main Author: Schaubel, Douglas E.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 15.10.2005; Wiley Subscription Services, Inc
• Subjects: Biomedical research; bootstrap; Canada; Cluster Analysis; clustered failure time data; Computer Simulation; Data analysis; Data Interpretation, Statistical; Hospitalization; Humans; jackknife; Models, Statistical; Multicenter Studies as Topic; Peritoneal Dialysis; proportional means model; Recurrence; recurrent events; Renal Insufficiency - therapy; robust variance; sandwich estimator; semi-parametric model; Statistics; United States; variance estimation; Canada; United States

Often in biomedical studies, the event of interest is recurrent and within‐subject events cannot usually be assumed independent. In semi‐parametric estimation of the proportional rates model, a working independence assumption leads to an estimating equation for the regression parameter vector, with...