Columnar Injection for Intracerebral Cell Therapy

• Published in: Operative neurosurgery (Hagerstown, Md.) Vol. 18; no. 3; pp. 321 - 328
• Main Authors: Schweitzer, Jeffrey S, Song, Bin, Leblanc, Pierre R, Feitosa, Melissa, Carter, Bob S, Kim, Kwang-Soo
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.03.2020; Wolters Kluwer Health, Inc
• Subjects: Analysis; Animals; Brain; Cell- and Tissue-Based Therapy; Concepts, Innovations and Techniques; Dopamine; Embryonic stem cells; Humans; Neurons; Neurosurgery; Parkinson's disease; Rats; Stem cells; Surgical techniques; Transplantation; Massachusetts; California; Dopaminergic neurons; Stereotaxy; Cell therapy

Abstract BACKGROUND Surgical implantation of cellular grafts into the brain is of increasing importance, as stem cell-based therapies for Parkinson and other diseases continue to develop. The effect of grafting technique on development and survival of the graft has received less attention. Rate and...