Case Report: Cyclophosphamide in COVID-19 - when an absolute contraindication is an absolute necessity [version 2; peer review: 2 approved]

• Published in: F1000 research Vol. 10; p. 829
• Main Authors: Bołtuć, Kamila, Bielejewska, Ada, Coloma-Millar, Alejandro, Dziugieł, Robert, Bociek, Arkadiusz, Perkowska-Ptasińska, Agnieszka, Jaroszyński, Andrzej
• Format: Journal Article
• Language: English
• Published: London Faculty of 1000 Ltd 2021; F1000 Research Limited; F1000 Research Ltd
• Subjects: Alveoli; Anemia; Antibiotics; Antineutrophil cytoplasmic antibodies; Biopsy; Blood pressure; Case Report; Case reports; Contraindications; Coronaviruses; Corticosteroids; COVID-19; Creatinine; Cyclophosphamide; Cytokines; Diagnosis; Disease; Dyspnea; Fever; Glomerulonephritis; Hemodialysis; Hemorrhage; Hospitalization; Immunoglobulins; Immunology; Immunotherapy; Infections; Intravenous administration; Kidneys; Laboratories; Leukocytes (neutrophilic); Lungs; Nephrology; Neutrophils; Patients; Pneumonia; Proteins; Respiration; Respiratory distress syndrome; Severe acute respiratory syndrome coronavirus 2; Tomography; Urine; Vasculitis; COVID-19; alveolar haemorrhage; cyclophosphamide; vasculitis; p-ANCA

Background: Despite many studies on COVID-19, our knowledge of it remains incomplete. In some cases, treating SARS-CoV-2 infection concomitant with other diseases can be particularly challenging, as finding an appropriate treatment may involve some risks. Case presentation: A 34-year-old SARS-CoV-2...