Analysis of Candidate miRNAs' Expression in Pancreatic Cancer

• Published in: Cancer medicine (Malden, MA) Vol. 13; no. 21; pp. e70400 - n/a
• Main Authors: Al‐Temaimi, Rabeah, Abdulkarim, Bicher, Al‐Ali, Ali, John, Bency, Mallik, Mrinmay Kumar, Kapila, Kusum
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.11.2024; Wiley
• Subjects: Adult; Aged; Biomarkers; Biomarkers, Tumor - genetics; Enzymes; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Human subjects; Humans; Immunocytochemistry; K-Ras protein; KRAS; Male; Medical diagnosis; Medical prognosis; MicroRNA; MicroRNAs; MicroRNAs - genetics; Middle Aged; miRNA; Morphology; Neoplasm Staging; NFKBIA; Pancreatic cancer; Pancreatic Neoplasms - genetics; Pancreatic Neoplasms - metabolism; Pancreatic Neoplasms - pathology; Pathogenesis; Physiology; Polyethylene glycol; Ribonucleic acid; RNA; Tumors; United States > US; NFKBIA; pancreatic cancer; KRAS; MicroRNA

ABSTRACT Background Pancreatic cancer (PC) is one of the most aggressive types of cancer. Despite advances in molecular diagnostics, PC diagnosis relies on imaging technologies and morphological assessment of fine needle aspirates (FNAs). MicroRNA (miRNA) involvement in PC pathogenesis and potential...