Efficacy of ketamine in relieving neuropathic pain: a systematic review and meta-analysis of animal studies

• Published in: Pain (Amsterdam) Vol. 162; no. 9; pp. 2320 - 2330
• Main Authors: Velzen, Monique van, Dahan, Jack D C, van Dorp, Eveline L A, Mogil, Jeffrey S, Hooijmans, Carlijn R, Dahan, Albert
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer 01.09.2021
• Subjects: Animals; Hyperalgesia - drug therapy; Ketamine - therapeutic use; Mice; Neuralgia - drug therapy; Rats; Systematic Review and Meta-Analysis

In humans, proof of long-term efficacy of ketamine treatment in neuropathic pain is lacking. To improve our understanding of ketamine behavior under various administration conditions, we performed a systematic review and meta-analyses of controlled studies on the efficacy of ketamine in mice and rat...