Spreadsheet-Based Program for Alignment of Overlapping DNA Sequences

• Published in: BioTechniques Vol. 26; no. 6; pp. 1180 - 1185
• Main Authors: Anbazhagan, Ramaswamy, Gabrielson, Edward
• Format: Journal Article
• Language: English
• Published: Natick, MA Future Science Ltd 01.06.1999; Eaton; Taylor & Francis Group
• Subjects: Base Sequence; Biological and medical sciences; Cloning, Molecular; Diverse techniques; DNA - analysis; DNA Primers; Fundamental and applied biological sciences. Psychology; General aspects; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Molecular and cellular biology; Molecular Sequence Data; Sequence Analysis, DNA - methods; Software; User-Computer Interface; Computer science; Alignment; Spreadsheet; Software; Overlap; Nucleotide sequence

Molecular biology laboratories frequently face the challenge of aligning small overlapping DNA sequences derived from a long DNA segment. Here, we present a short program that can be used to adapt Excel spreadsheets as a tool for aligning DNA sequences, regardless of their orientation. The program r...